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BRCA2: One Small Step for DNA Repair, One Giant Protein Purified

DNA damage, malfunctions in DNA repair, and genomic instability are processes that intersect at the crossroads of carcinogenesis. Underscoring the importance of DNA repair in breast and ovarian tumorigenesis is the familial inherited cancer predisposition gene BRCA2. The role of BRCA2 in DNA double-...

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Bibliographic Details
Main Author: Jensen, Ryan B.
Format: Artigo
Language:Inglês
Published: YJBM 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848102/
https://ncbi.nlm.nih.gov/pubmed/24348212
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