Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries

Comprehensive identification of sequences that regulate transcription is one of the major goals of genome biology. Focal alteration in chromatin structure in vivo, detectable through hypersensitivity to DNaseI and other nucleases, is the sine qua non of a diverse cast of transcriptional regulatory e...

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Главные авторы: Sabo, Peter J., Humbert, Richard, Hawrylycz, Michael, Wallace, James C., Dorschner, Michael O., McArthur, Michael, Stamatoyannopoulos, John A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC384782/
https://ncbi.nlm.nih.gov/pubmed/15070753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400678101
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