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Disclosing the crosstalk among DNA methylation, transcription factors, and histone marks in human pluripotent cells through discovery of DNA methylation motifs

Gene expression regulation is gated by promoter methylation states modulating transcription factor binding. The known DNA methylation/unmethylation mechanisms are sequence unspecific, but different cells with the same genome have different methylomes. Thus, additional processes bringing specificity...

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Detalhes bibliográficos
Main Authors: Luu, Phuc-Loi, Schöler, Hans R., Araúzo-Bravo, Marcos J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847772/
https://ncbi.nlm.nih.gov/pubmed/24149073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.155960.113
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