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Oral Toxicity of Okadaic Acid in Mice: Study of Lethality, Organ Damage, Distribution and Effects on Detoxifying Gene Expression

In vivo, after administration by gavage to mice and rats, okadaic acid has been reported to produce lesions in liver, small intestine and forestomach. Because several reports differ in the damage detected in different organs, and on okadaic acid distribution after consumption, we determined the toxi...

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Detalhes bibliográficos
Main Authors: Vieira, Andres C., Rubiolo, Juan A., López-Alonso, Henar, Cifuentes, José Manuel, Alfonso, Amparo, Bermúdez, Roberto, Otero, Paz, Vieytes, Mercedes R., Vega, Félix V., Botana, Luis M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847716/
https://ncbi.nlm.nih.gov/pubmed/24217398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins5112093
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