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A transgenic mouse model of metastatic carcinoma involving transdifferentiation of a gastric epithelial lineage progenitor to a neuroendocrine phenotype

Human neuroendocrine cancers (NECs) arise in various endoderm-derived epithelia, have diverse morphologic features, exhibit a wide range of growth phenotypes, and generally have obscure cellular origins and ill-defined molecular mediators of initiation and progression. We describe a transgenic mouse...

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Detalhes bibliográficos
Main Authors: Syder, Andrew J., Karam, Sherif M., Mills, Jason C., Ippolito, Joseph E., Ansari, Habib R., Farook, Vidya, Gordon, Jeffrey I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384771/
https://ncbi.nlm.nih.gov/pubmed/15070742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307983101
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