A transgenic mouse model of metastatic carcinoma involving transdifferentiation of a gastric epithelial lineage progenitor to a neuroendocrine phenotype

Human neuroendocrine cancers (NECs) arise in various endoderm-derived epithelia, have diverse morphologic features, exhibit a wide range of growth phenotypes, and generally have obscure cellular origins and ill-defined molecular mediators of initiation and progression. We describe a transgenic mouse...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Syder, Andrew J., Karam, Sherif M., Mills, Jason C., Ippolito, Joseph E., Ansari, Habib R., Farook, Vidya, Gordon, Jeffrey I.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2004
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15070742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307983101
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