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Genome-wide Measurement of RNA Secondary Structure in Yeast

The structures of RNA molecules are often important for their function and regulation(1-6), yet there are no experimental techniques for genome-scale measurement of RNA structure. Here, we describe a novel strategy termed Parallel Analysis of RNA Structure (PARS), which is based on deep sequencing f...

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Autors principals: Kertesz, Michael, Wan, Yue, Mazor, Elad, Rinn, John L., Nutter, Robert C., Chang, Howard Y., Segal, Eran
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847670/
https://ncbi.nlm.nih.gov/pubmed/20811459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09322
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