Chargement en cours...
Expression of integrin alpha 10 is transcriptionally activated by pRb in mouse osteoblasts and is downregulated in multiple solid tumors
pRb is known as a classic cell cycle regulator whose inactivation is an important initiator of tumorigenesis. However, more recently, it has also been linked to tumor progression. This study defines a role for pRb as a suppressor of the progression to metastasis by upregulating integrin α10. Transcr...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2013
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3847337/ https://ncbi.nlm.nih.gov/pubmed/24287699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.461 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|