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The herpes simplex virus major regulatory protein ICP4 blocks apoptosis induced by the virus or by hyperthermia.

Cells infected with herpes simplex virus 1 (HSV-1) undergo productive or latent infection without exhibiting features characteristic of apoptosis. In this report, we show that HSV-1 induces apoptosis but has evolved a function that blocks apoptosis induced by infection as well as by other means. Spe...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Leopardi, R, Roizman, B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38471/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9583
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