Monoacylglycerols Activate TRPV1 – A Link between Phospholipase C and TRPV1

Phospholipase C-mediated hydrolysis of phosphatidylinositol 4,5-bisphosphate generates diacylglycerol, inositol 1,4,5-trisphosphate and protons, all of which can regulate TRPV1 activity via different mechanisms. Here we explored the possibility that the diacylglycerol metabolites 2-arachidonoylglyce...

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Autori principali: Zygmunt, Peter M., Ermund, Anna, Movahed, Pouya, Andersson, David A., Simonsen, Charlotte, Jönsson, Bo A. G., Blomgren, Anders, Birnir, Bryndis, Bevan, Stuart, Eschalier, Alain, Mallet, Christophe, Gomis, Ana, Högestätt, Edward D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847081/
https://ncbi.nlm.nih.gov/pubmed/24312564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081618
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