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Human Omental-Derived Adipose Stem Cells Increase Ovarian Cancer Proliferation, Migration, and Chemoresistance

OBJECTIVES: Adipose tissue contains a population of multipotent adipose stem cells (ASCs) that form tumor stroma and can promote tumor progression. Given the high rate of ovarian cancer metastasis to the omental adipose, we hypothesized that omental-derived ASC may contribute to ovarian cancer growt...

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Huvudupphovsmän: Nowicka, Aleksandra, Marini, Frank C., Solley, Travis N., Elizondo, Paula B., Zhang, Yan, Sharp, Hadley J., Broaddus, Russell, Kolonin, Mikhail, Mok, Samuel C., Thompson, Melissa S., Woodward, Wendy A., Lu, Karen, Salimian, Bahar, Nagrath, Deepak, Klopp, Ann H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847080/
https://ncbi.nlm.nih.gov/pubmed/24312594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081859
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