Apoptosis mediated by HIV protease is preceded by cleavage of Bcl-2.

Expression of the human immunodeficiency virus type 1 (HIV) protease in cultured cells leads to apoptosis, preceded by cleavage of bcl-2, a key negative regulator of cell death. In contrast, a high level of bcl-2 protects cells in vitro and in vivo from the viral protease and prevents cell death fol...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Strack, P R, Frey, M W, Rizzo, C J, Cordova, B, George, H J, Meade, R, Ho, S P, Corman, J, Tritch, R, Korant, B D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38469/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9571
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