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Clinical utility of the combination of lapatinib and letrozole in the management of hormone receptor-positive and HER2-positive advanced breast cancer

Breast cancers that overexpress human epidermal growth factor receptor-2 (HER2-positive [HER2+]) tend to be biologically aggressive and associated with a poor prognosis, even those that coexpress receptors for estrogen and/or progesterone (hormone receptor-positive [HR+]). Optimal therapy for patien...

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Autors principals: Merriam, Priscilla, Sikov, William M
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846896/
https://ncbi.nlm.nih.gov/pubmed/24367183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S12150
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