Effect of DNA methylation inhibitor on RASSF1A genes expression in non-small cell lung cancer cell line A549 and A549DDP

BACKGROUND: Ras association domain family 1A gene (RASSFlA) is a candidate suppressor gene, Lack of RASSF1A expression was found in lung cancer. High DNA methylation at the promoter region is the main reason for inactivating RASSF1A transcription. METHODS: In this study, we examined RASSF1A’s methyl...

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Bibliographic Details
Main Authors: Mengxi, Duan, Qian, Wang, Nan, Wang, Xiaoguang, Xiao, Shijun, Li
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
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Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846638/
https://ncbi.nlm.nih.gov/pubmed/24011511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-91
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