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NMR studies of the relationship between the changes of membrane lipids and the cisplatin-resistance of A549/DDP cells

Changes of membrane lipids in cisplatin-sensitive A549 and cisplatin-resistant A549/DDP cells during the apoptotic process induced by a clinical dose of cisplatin (30 μM) were detected by (1)H and (31)P-NMR spectroscopy and by membrane fluidity measurement. The apoptotic phenotypes of the two cell l...

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Hlavní autoři: Huang, Zhenhua, Tong, Yufeng, Wang, Jinfeng, Huang, Youguo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC154102/
https://ncbi.nlm.nih.gov/pubmed/12718757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-3-5
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