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Stereotaxic Microinjection of Viral Vectors Expressing Cre Recombinase to Study the Role of Target Genes in Cocaine Conditioned Place Preference

Microinjecting recombinant adenoassociated viral (rAAV) vectors expressing Cre recombinase into distinct mouse brain regions to selectively knockout genes of interest allows for enhanced temporally- and regionally-specific control of gene deletion, compared to existing methods. While conditional del...

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Autors principals: Schierberl, Kathryn C., Rajadhyaksha, Anjali M.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846586/
https://ncbi.nlm.nih.gov/pubmed/23929203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50600
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