Prospective Validation of Immunological Infiltrate for Prediction of Response to Neoadjuvant Chemotherapy in HER2-Negative Breast Cancer – A Substudy of the Neoadjuvant GeparQuinto Trial

INTRODUCTION: We have recently described an increased lymphocytic infiltration rate in breast carcinoma tissue is a significant response predictor for anthracycline/taxane-based neoadjuvant chemotherapy (NACT). The aim of this study was to prospectively validate the tumor-associated lymphocyte infil...

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Hauptverfasser: Issa-Nummer, Yasmin, Darb-Esfahani, Silvia, Loibl, Sibylle, Kunz, Georg, Nekljudova, Valentina, Schrader, Iris, Sinn, Bruno Valentin, Ulmer, Hans-Ullrich, Kronenwett, Ralf, Just, Marianne, Kühn, Thorsten, Diebold, Kurt, Untch, Michael, Holms, Frank, Blohmer, Jens-Uwe, Habeck, Jörg-Olaf, Dietel, Manfred, Overkamp, Friedrich, Krabisch, Petra, von Minckwitz, Gunter, Denkert, Carsten
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846472/
https://ncbi.nlm.nih.gov/pubmed/24312450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079775
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