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Role of pertuzumab in the treatment of HER2-positive breast cancer

Pertuzumab, a humanized monoclonal antibody to the HER2 receptor, represents a promising new anti-HER2 agent with a novel mechanism of action targeting the inhibition of HER2 dimerization. Nonclinical and clinical data to date indicate that pertuzumab provides a broader HER2 blockade through the inh...

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Detalhes bibliográficos
Main Authors: Hubalek, Michael, Brantner, Christine, Marth, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846374/
https://ncbi.nlm.nih.gov/pubmed/24367194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S23560
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