Synthesis and biological evaluation of novel benzyl piperazine derivatives of 5-(5-nitroaryl)-1,3,4-thiadiazoles as Anti-Helicobacter pylori agents

BACKGROUND AND THE PURPOSE OF THE STUDY: Helicobacter pylori is recognized as the main cause of gastritis and gastroduodenal ulcers and classified as class 1 carcinogen pathogen. Different 1,3,4-thiadiazole derivatives bearing 5-nitroaryl moiety have been shown considerable anti- H. pylori activity....

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Main Authors: Mohammadhosseini, Negar, Saniee, Parastoo, Ghamaripour, Ameneh, Aryapour, Hassan, Afshar, Farzaneh, Edraki, Najmeh, Siavoshi, Farideh, Foroumadi, Alireza, Shafiee, Abbas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846157/
https://ncbi.nlm.nih.gov/pubmed/23924894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2008-2231-21-66
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