Application of lactobionic acid and nonionic surfactants as solubilizing agents for parenteral formulation of clarithromycin

Purpose: The purpose of this paper is to enhance the solubility of clarithromycin (CLR) using nonionic surfactants and some type of acids for preparation of the new formulations. Methods: Myrj 52 and chremophor (2.5 and 5% w/v) were used in two concentrations. To investigate solubility, the formulat...

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Bibliographic Details
Main Authors: Zakeri-Milani, Parvin, Mousavian-Fathi, Niaz, Ghanbarzadeh, Saeed, Zarrintan, Mohammad-Hosein, Valizadeh, Hadi
Format: Artigo
Language:Inglês
Published: Tabriz University of Medical Sciences 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846005/
https://ncbi.nlm.nih.gov/pubmed/24312769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5681/apb.2012.006
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