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Synthesis and Pharmacological Evaluation of Some New Pyrimidine Derivatives Containing 1,2,4-Triazole

Purpose: An efficient method has been described for synthesis of 6-(substituted aryl)-4-(3,5-diphenyl-1H-1,2,4-triazol-1-yl)-1, 6-dihydropyrimidine-2-thiol, as a beneficial antimicrobial, anticonvulsant and anticancer agents. Methods: The clalcones of title compounds were synthesized in three steps...

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Détails bibliographiques
Auteurs principaux: Khanage, Shantaram Gajanan, Raju, S. Appala, Mohite, Popat Baban, Pandhare, Ramdas Bhanudas
Format: Artigo
Langue:Inglês
Publié: Tabriz University of Medical Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3846002/
https://ncbi.nlm.nih.gov/pubmed/24312796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5681/apb.2012.033
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