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Propofol Stimulates Noradrenalin-Inhibited Neurons in the Ventrolateral Preoptic Nucleus by Reducing GABAergic Inhibition

BACKGROUND: The cellular mechanisms underlying the sedative effect of general anesthetics are not completely understood. Accumulating evidence indicates that the ventrolateral preoptic area (VLPO) of the hypothalamus plays a critical role. The VLPO contains two major types of neurons, the noradrenal...

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Bibliographic Details
Main Authors: Liu, Yu-Wei, Zuo, Wanhong, Ye, Jiang-Hong
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845501/
https://ncbi.nlm.nih.gov/pubmed/23780420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e318297366e
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