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Comparative proteomic analysis of the aging soleus and extensor digitorum longus rat muscles using TMT labeling and mass spectrometry

Sarcopenia describes an age-related decline in skeletal muscle mass, strength, and function that ultimately impairs metabolism, leads to poor balance, frequent falling, limited mobility, and a reduction in quality of life. Here we investigate the pathogenesis of sarcopenia through a proteomic shotgu...

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Bibliographic Details
Main Authors: Chaves, Daniela F. S., Carvalho, Paulo C., Lima, Diogo B., Nicastro, Humberto, Lorenzetti, Fábio M., Filho, Mário S., Hirabara, Sandro M., Alves, Paulo H. M., Moresco, James J., Yates, John R., Lancha, Antonio H.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845496/
https://ncbi.nlm.nih.gov/pubmed/24001182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr400644x
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