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Thrombospondin-1 Silencing Down-Regulates Integrin Expression Levels in Human Anaplastic Thyroid Cancer Cells with BRAF(V600E): New Insights in the Host Tissue Adaptation and Homeostasis of Tumor Microenvironment

Background and Rationale: Anaplastic thyroid cancer (ATC) is characterized by pleomorphic cells, has a poor prognosis, is highly devastating disease, and is not curable. No reliable biomarkers of metastatic potential, helpful for early diagnosis of ATC and therapeutic response have been found yet. T...

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Detalhes bibliográficos
Main Authors: Duquette, Mark, Sadow, Peter M., Lawler, Jack, Nucera, Carmelo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845490/
https://ncbi.nlm.nih.gov/pubmed/24348463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2013.00189
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