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CRYO-EM STRUCTURES OF THE ACTIN:TROPOMYOSIN FILAMENT REVEAL THE MECHANISM FOR THE TRANSITION FROM C- TO M-STATE

Tropomyosin is a key factor in the molecular mechanisms that regulate the binding of myosin motors to actin filaments in most eukaryotic cells. This regulation is achieved by the azimuthal repositioning of tropomyosin along the actin:tropomyosin:troponin thin filament to block or expose myosin bindi...

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Detalhes bibliográficos
Main Authors: Sousa, Duncan R., Stagg, Scott M., Stroupe, M. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845445/
https://ncbi.nlm.nih.gov/pubmed/24021812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.08.020
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