Selection on hemagglutinin imposes a bottleneck during mammalian transmission of reassortant H5N1 influenza viruses

The emergence of human-transmissible H5N1 avian influenza viruses poses a major pandemic threat. H5N1 viruses are thought to be highly genetically diverse both among and within hosts, but the effects of this diversity on viral replication and transmission are poorly understood. Here we use deep sequ...

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Detaylı Bibliyografya
Asıl Yazarlar: Wilker, Peter R., Dinis, Jorge M., Starrett, Gabriel, Imai, Masaki, Hatta, Masato, Nelson, Chase W., O’Connor, David H., Hughes, Austin L., Neumann, Gabriele, Kawaoka, Yoshihiro, Friedrich, Thomas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845350/
https://ncbi.nlm.nih.gov/pubmed/24149915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3636
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