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Population pharmacokinetics of recombinant human C1 inhibitor in patients with hereditary angioedema
AIMS: To characterize the pharmacokinetics (PK) of recombinant human C1 inhibitor (rhC1INH) in healthy volunteers and hereditary angioedema (HAE) patients. METHODS: Plasma levels of C1INH following 294 administrations of rhC1INH in 133 subjects were fitted using nonlinear mixed-effects modelling. Th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3845313/ https://ncbi.nlm.nih.gov/pubmed/23594263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12132 |
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