NKT Cells as an Ideal Anti-Tumor Immunotherapeutic

Human natural killer T (NKT) cells are characterized by their expression of an invariant T cell antigen receptor α chain variable region encoded by a Vα24Jα18 rearrangement. These NKT cells recognize α-galactosylceramide (α-GalCer) in conjunction with the MHC class I-like CD1d molecule and bridge th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fujii, Shin-ichiro, Shimizu, Kanako, Okamoto, Yoshitaka, Kunii, Naoki, Nakayama, Toshinori, Motohashi, Shinichiro, Taniguchi, Masaru
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845015/
https://ncbi.nlm.nih.gov/pubmed/24348476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00409
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