Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures

Listeria can escape host autophagy defense pathways through mechanisms that remain poorly understood. We show here that in epithelial cells, Listeriolysin (LLO)-dependent cytosolic escape of Listeria triggered a transient amino-acid starvation host response characterized by GCN2 phosphorylation, ATF...

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Detaylı Bibliyografya
Asıl Yazarlar: Tattoli, Ivan, Sorbara, Matthew T, Yang, Chloe, Tooze, Sharon A, Philpott, Dana J, Girardin, Stephen E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: European Molecular Biology Organization 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844955/
https://ncbi.nlm.nih.gov/pubmed/24162724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.234
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