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Diosgenin-induced cognitive enhancement in normal mice is mediated by 1,25D(3)-MARRS

We previously reported that diosgenin, a plant-derived steroidal sapogenin, improved memory and reduced axonal degeneration in an Alzheimer's disease mouse model. Diosgenin directly activated the membrane-associated rapid response steroid-binding receptor (1,25D(3)-MARRS) in neurons. However, 1...

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Detalhes bibliográficos
Main Authors: Tohda, Chihiro, Lee, Young-A, Goto, Yukiori, Nemere, Ilka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844946/
https://ncbi.nlm.nih.gov/pubmed/24292207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03395
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