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Biological constraints limit the use of rapamycin-inducible FKBP12-Inp54p for depleting PIP(2) in dorsal root ganglia neurons
BACKGROUND: Rapamycin-induced translocation systems can be used to manipulate biological processes with precise temporal control. These systems are based on rapamycin-induced dimerization of FK506 Binding Protein 12 (FKBP12) with the FKBP Rapamycin Binding (FRB) domain of mammalian target of rapamyc...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844522/ https://ncbi.nlm.nih.gov/pubmed/24010830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-12-13 |
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