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Whirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axons

BACKGROUND: Myelinated axons are organized into distinct subcellular and molecular regions. Without proper organization, electrical nerve conduction is delayed, resulting in detrimental physiological outcomes. One such region is the paranode where axo-glial septate junctions act as a molecular fence...

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Detalhes bibliográficos
Main Authors: Green, James A, Yang, Jun, Grati, M’hamed, Kachar, Bechara, Bhat, Manzoor A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844453/
https://ncbi.nlm.nih.gov/pubmed/24011083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-96
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