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A HAPTEN GENERATED FROM AN OXIDATION FRAGMENT OF DOCOSAHEXAENOIC ACID IS SUFFICIENT TO INITIATE AGE-RELATED MACULAR DEGENERATION
The protien adduct carboxyethylpyrrole (CEP) is present in AMD eye tissue and in the blood of AMD patients at higher levels than found in age matched non-AMD tissues. Autoantibodies to CEP are also higher in AMD blood samples than in controls. To test the hypothesis that this hapten is causally invo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3844284/ https://ncbi.nlm.nih.gov/pubmed/20221855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-010-8110-z |
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