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Accelerated Aging during Chronic Oxidative Stress: A Role for PARP-1

Oxidative stress plays a major role in the pathophysiology of chronic inflammatory disease and it has also been linked to accelerated telomere shortening. Telomeres are specialized structures at the ends of linear chromosomes that protect these ends from degradation and fusion. Telomeres shorten wit...

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書誌詳細
主要な著者: Boesten, Daniëlle M. P. H. J., de Vos-Houben, Joyce M. J., Timmermans, Leen, den Hartog, Gertjan J. M., Bast, Aalt, Hageman, Geja J.
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844163/
https://ncbi.nlm.nih.gov/pubmed/24319532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/680414
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