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A Novel Role of Nucleostemin in Maintaining the Genome Integrity of Dividing Hepatocytes During Mouse Liver Development and Regeneration

During liver development and regeneration, hepatocytes undergo rapid cell division and face an increased risk of DNA damage associated with active DNA replication. The mechanism that protects proliferating hepatocytes from replication-induced DNA damage remains unclear. Nucleostemin (NS) is known to...

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Hlavní autoři: Lin, Tao, Ibrahim, Wessam, Peng, Cheng-Yuan, Finegold, Milton J, Tsai, Robert Y.L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844114/
https://ncbi.nlm.nih.gov/pubmed/23813570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26600
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