Pregnancy specific glycoprotein 1 (PSG1) activates TGF-β and prevents dextran sodium sulfate (DSS)-induced colitis in mice

Transforming growth factor beta (TGF-βs) are secreted from cells as latent complexes and the activity of TGF-βs is controlled predominantly through activation of these complexes. Tolerance to the fetal allograft is essential for pregnancy success; TGF-β1 and -β2 play important roles in regulating th...

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Main Authors: Blois, Sandra M., Sulkowski, Gisela, Tirado-González, Irene, Warren, James, Freitag, Nancy, Klapp, Burghard F., Rifkin, Daniel, Fuss, Ivan, Strober, Warren, Dveksler, Gabriela S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844031/
https://ncbi.nlm.nih.gov/pubmed/23945545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.53
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