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Host Pigment Epithelium-Derived Factor (PEDF) Prevents Progression of Uveal Melanoma Metastasis in the Liver

Uveal melanoma (UM) has a 30% five-year mortality rate, primarily due to liver metastasis. Both angiogenesis and stromagenesis are important mechanisms for the progression of liver metastasis. Pigment epithelium-derived factor (PEDF), an anti-angiogenic and anti-stromagenic protein, is produced by h...

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Detalhes bibliográficos
Main Authors: Lattier, John M., Yang, Hua, Crawford, Susan, Grossniklaus, Hans E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3844008/
https://ncbi.nlm.nih.gov/pubmed/23793989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-013-9596-3
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