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Relaxin Decreases the Severity of Established Hepatic Fibrosis in Mice

BACKGROUND: Hepatic fibrosis is characterized by excess collagen deposition, decreased extracellular matrix degradation, and activation of the hepatic stellate cells. The hormone relaxin has shown promise in the treatment of fibrosis in a number of tissues, but the effect of relaxin on established h...

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Detalhes bibliográficos
Main Authors: Bennett, Robert G., Heimann, Dean G., Singh, Sudhir, Simpson, Ronda L., Tuma, Dean J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843971/
https://ncbi.nlm.nih.gov/pubmed/23870027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12247
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