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Life-Threatening Gastrointestinal Mucosal Necrosis during Methotrexate Treatment for Rheumatoid Arthritis

Methotrexate (MTX), a folic acid antagonist, is widely used in the treatment of neoplasms, psoriasis and rheumatoid arthritis. Despite its efficacy, MTX sometimes finds limited application because of its adverse effects, including renal or liver impairment, bone marrow toxicity and gastrointestinal...

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Bibliographic Details
Main Authors: Tsukada, Tomoya, Nakano, Tatsuo, Miyata, Takashi, Sasaki, Shozo
Format: Artigo
Language:Inglês
Published: S. Karger AG 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843920/
https://ncbi.nlm.nih.gov/pubmed/24348319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000356817
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