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Life-Threatening Gastrointestinal Mucosal Necrosis during Methotrexate Treatment for Rheumatoid Arthritis

Methotrexate (MTX), a folic acid antagonist, is widely used in the treatment of neoplasms, psoriasis and rheumatoid arthritis. Despite its efficacy, MTX sometimes finds limited application because of its adverse effects, including renal or liver impairment, bone marrow toxicity and gastrointestinal...

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Main Authors: Tsukada, Tomoya, Nakano, Tatsuo, Miyata, Takashi, Sasaki, Shozo
格式: Artigo
語言:Inglês
出版: S. Karger AG 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843920/
https://ncbi.nlm.nih.gov/pubmed/24348319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000356817
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