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Alternative polyadenylation and differential expression of Shank mRNAs in the synaptic neuropil

The stability and dynamics of synapses rely on tight regulation of the synaptic proteome. Shank proteins, encoded by the three genes Shank1, Shank2 and Shank3 are scaffold molecules in the postsynaptic density of excitatory neurons that contribute to activity-dependent neuronal signalling. Mutations...

詳細記述

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書誌詳細
主要な著者: Epstein, Irina, Tushev, Georgi, Will, Tristan J., Vlatkovic, Irena, Cajigas, Iván J., Schuman, Erin M.
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843870/
https://ncbi.nlm.nih.gov/pubmed/24298140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0137
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