RhoE Promotes Metastasis in Gastric Cancer through a Mechanism Dependent on Enhanced Expression of CXCR4

RhoE, a novel member of the Rho protein family, is a key regulator of the cytoskeleton and cell migration. Our group has previously shown that RhoE as a direct target for HIF-1α and mediates hypoxia-induced epithelial to mesenchymal transition in gastric cancer cells. Therefore, we assumed that RhoE...

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Detalhes bibliográficos
Main Authors: Feng, Bin, Li, Kai, Zhong, Haixing, Ren, Gui, Wang, Hefei, Shang, Yulong, Bai, Ming, Liang, Jie, Wang, Xin, Fan, Daiming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843694/
https://ncbi.nlm.nih.gov/pubmed/24312338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081709
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