The propeptide of macrophage inhibitory cytokine (MIC-1), a TGF-β superfamily member, acts as a quality control determinant for correctly folded MIC-1

Macrophage inhibitory cytokine (MIC-1), a divergent member of the transforming growth factor-β (TGF-β) superfamily and activation associated cytokine, is secreted as a 28 kDa dimer. To understand its secretion, we examined its processing in MIC-1-transfected Chinese hamster ovary cells. Mature MIC-1...

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Detalhes bibliográficos
Main Authors: Bauskin, Asne R., Zhang, Hong-Ping, Fairlie, W.Douglas, He, Xiao Yan, Russell, Patricia K., Moore, Anthony G., Brown, David A., Stanley, Keith K., Breit, Samuel N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC384362/
https://ncbi.nlm.nih.gov/pubmed/10811612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.10.2212
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