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Sorafenib inhibits liver regeneration in rats

BACKGROUND: Sorafenib is a multikinase inhibitor with antiangiogenic and antiproliferative properties, approved for the treatment of hepatocellular carcinoma. The effect of Sorafenib on liver regeneration in healthy rats was investigated. METHODS: Sixty Wistar rats received either Sorafenib (group S...

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Detalhes bibliográficos
Main Authors: Andersen, Kasper Jarlhelt, Knudsen, Anders Riegels, Kannerup, Anne-Sofie, Sasanuma, Hideki, Nyengaard, Jens Randel, Hamilton-Dutoit, Stephen, Ladekarl, Morten, Mortensen, Frank Viborg
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843612/
https://ncbi.nlm.nih.gov/pubmed/23461776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hpb.12068
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