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Anti-inflammatory IL-10 is upregulated in both hemispheres after experimental ischemic stroke: Hypertension blunts the response

BACKGROUND: Exogenous administration of the anti-inflammatory cytokine, interleukin 10 (IL-10), is known to promote neuroprotection and mitigate neuroinflammation after ischemia. However, endogenous expression and localization of IL-10 and its receptor (IL-10R) in the post-ischemic brain are still t...

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Detalhes bibliográficos
Main Authors: Fouda, Abdelrahman Y, Kozak, Anna, Alhusban, Ahmed, Switzer, Jeffrey A, Fagan, Susan C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843530/
https://ncbi.nlm.nih.gov/pubmed/24499655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-7378-5-12
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