Regulation of 130-kDa Smooth Muscle Myosin Light Chain Kinase Expression by an Intronic CArG Element

The mylk1 gene encodes a 220-kDa nonmuscle myosin light chain kinase (MLCK), a 130-kDa smooth muscle MLCK (smMLCK), as well as the non-catalytic product telokin. Together, these proteins play critical roles in regulating smooth muscle contractility. Changes in their expression are associated with ma...

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Autors principals: Chen, Meng, Zhang, Wenwu, Lu, Xiao, Hoggatt, April M., Gunst, Susan J., Kassab, Ghassan S., Tune, Johnathan D., Herring, B. Paul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843077/
https://ncbi.nlm.nih.gov/pubmed/24151072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.510362
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