Amphotericin B selection of mutant Chinese hamster cells with defects in the receptor-mediated endocytosis of low density lipoprotein and cholesterol biosynthesis.

This paper describes a rapid and efficient two-step procedure for the isolation of mutant cells with defects in receptor-mediated endocytosis. The procedure takes advantage of two fungal metabolites, compactin (ML236B), a potent inhibitor of cholesterol biosynthesis, and amphotericin B, a polyene an...

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Autori principali: Krieger, M, Martin, J, Segal, M, Kingsley, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1983
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC384307/
https://ncbi.nlm.nih.gov/pubmed/6310583
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