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1 alpha,25-dihydroxyvitamin D3 promotes fusion of mouse alveolar macrophages both by a direct mechanism and by a spleen cell-mediated indirect mechanism.

Extensive fusion was induced in mouse alveolar macrophages by treatment with conditioned media obtained from spleen cell cultures treated with 15 micrograms of phytohemagglutinin or concanavalin A per ml or with 12 nM 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3]. The fusion rate was 80-90% on...

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Main Authors: Abe, E, Miyaura, C, Tanaka, H, Shiina, Y, Kuribayashi, T, Suda, S, Nishii, Y, DeLuca, H F, Suda, T
Formato: Artigo
Idioma:Inglês
Publicado: 1983
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC384302/
https://ncbi.nlm.nih.gov/pubmed/6577445
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