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Mapping Brain Metals to Evaluate Therapies for Neurodegenerative Disease
The brain is rich in metals and has a high metabolic rate, making it acutely vulnerable to the toxic effects of endogenously produced free radicals. The abundant metals, iron and copper, transfer single electrons as they cycle between their reduced (Fe(2+), Cu(1+)) and oxidized (Fe(3+), Cu(2+)) stat...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3843008/ https://ncbi.nlm.nih.gov/pubmed/20553312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-5949.2010.00149.x |
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