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Experimental Sepsis Impairs Humoral Memory in Mice

Patients with sepsis are often immune suppressed, and experimental mouse models of sepsis also display this feature. However, acute sepsis in mice is also characterized by a generalized B cell activation and plasma cell differentiation, resulting in a marked increase in serum antibody concentration....

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Detalhes bibliográficos
Main Authors: Pötschke, Christian, Kessler, Wolfram, Maier, Stefan, Heidecke, Claus-Dieter, Bröker, Barbara M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842948/
https://ncbi.nlm.nih.gov/pubmed/24312349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081752
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