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Slow cruciform transitions in palindromic DNA.

Extrusion of cruciform structures in self-complementary regions of DNA is known to be favored by negative supercoiling of DNA. We show here that, in moderately supercoiled DNA, cruciform extrusion is a very slow process. In plasmid pUC7 DNA, with a 48-base-pair palindrome, the half-time of extrusion...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Gellert, M, O'Dea, M H, Mizuuchi, K
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1983
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384294/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6577442/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.18.5545
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